L-leucine-dehydrogenase

EC 1.4.1.9

Oxidoreductase

from Bacillus cereus

Application: L-leucine-dehydrogenase is a product that catalyses the oxidative deamination of L-leucine, L-valine und L-isoleucine as well as of amino acids with unbranched-chained aliphatic carbonic chain. Caused by the reverse reaction a lot of 2-ketoacids in particular 2-isocapronate, 2-ketoisovalerate and 2-keto-3-methylvalerate with 0.9 M ammonium were aminated reductively to the corresponding amino acid..

Activity: > 50 U/mL

Article No.: 1410

Product data sheet DE: LeucinDH – 1410 – DE

Product data sheet ENG: LeucinDH – 1410 – ENG

Material safety data sheet: On inquiry

Scientific literature: 

The distribution and substrate specificity of l-leucine dehydrogenase (By M.W. Zink, B.D. Sanwal; 1962; Archives of Biochemistry and Biophysics, Volume 99, Issue 1, October 1962, Pages 72-77; DOI: 10.1016/0003-9861(62)90245-X)

Structural insights into thermostabilization of leucinedehydrogenase from its atomic structure by cryo-electron microscopy (By Hiroki Yamaguchi, Akiko Kamegawa, et al; 2019; Journal of Structal Biology, Volume 205, Issue 1, January 2019, Pages 11-21; DOI: 10.1016/j.jsb.2018.12.001)